関連する実験動画
Updated: Jun 30, 2026

08:25
Analysis of Coronary Vessels in Cleared Embryonic Hearts
Published on: December 7, 2016
まとめ
この研究は,健康な子供のための通常のエコーカルディオグラフィック測定を提供し,心臓の寸法と機能の基準範囲を確立します. これらの小児エコーカルディオグラフィーデータは,小児の心臓病の診断とモニタリングに役立ちます.
科学分野:
- ペディアトリック・カルディオロジー
- エコーカルディオグラフィー エコーカルディオグラフィー
- 心臓生理学 心臓生理学
背景:
- 標準的なエコーカルディオグラフィのデータを確立することは,小児の正確な心臓診断に不可欠です.
- 心臓の寸法と機能の変動は,異なる年齢層と子供の体のサイズによって存在します.
研究 の 目的:
- 幼児期から成人期までの小児患者の正常なエコーカルディオグラフィック測定を確立するために.
- 弁の運動,心腔の寸法,大血管直径,心室壁の厚さの基準範囲を定義する.
主な方法:
- 標準化されたプロトコルを用いて205人の健康な子供にエコーカルディオグラムを施しました.
- 中心室の寸法,壁の厚さ,大きな血管直径,弁の運動を含む心臓の重要なパラメータを測定しました.
- 身体表面積に基づいてデータを5,50,95のパーセンチルに分類した.
主要な成果:
- 身体表面積によって層分された包括的なエコーカルディオグラフィック測定を提示しました.
- パーセンチルベースのグラフを開発し,個々の患者の測定値を通常の基準と比較しました.
- 左心室と右心室の寸法,隔膜壁と自由壁の厚さ,大動脈の直径に関する規範的なデータを提供した.
結論:
- 確立された基準範囲は,小児の集団におけるエコーカルジオグラムの解釈を容易にする.
- この研究は,臨床医が心臓の健康を評価し,子供の異常を特定するために貴重なツールを提供します.
- 標準的なエコーカルディオグラフィのデータは,小児性心血管疾患の正確な診断と管理に不可欠です.
関連する概念動画
Blood Flow
Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
Chambers of the Heart
The human heart is a complex organ made up of four chambers: the right and left atria and the right and left ventricles. These internal chambers are separated by partitions known as the interatrial and interventricular septa. The exterior of the heart features a groove known as the coronary sulcus that demarcates the atria from the ventricles, while the anterior and posterior interventricular sulci distinguish between the two ventricles.
Deoxygenated blood from the body is received in the right...
Deoxygenated blood from the body is received in the right...
Heart Valves
The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
Development of the Heart
The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart tube by...
Structure of Blood Vessels
Blood is circulated throughout the human body through a network of blood vessels called the circulatory system. This system includes arteries that transport blood from the heart to various body parts. These arterial pathways divide into smaller vessels until they reach the arterioles, which further split into capillaries. It is within these minuscule capillaries that the exchange of nutrients and waste products takes place. After this exchange, the blood is collected by venules, which fuse to...
Development of Blood Vessels
The development of the vascular system in a fetus is a complex and intricate process that begins as early as 15 to 16 days post-conception. This process starts outside the embryo, specifically in the mesoderm of the yolk sac, chorion, and connecting stalk. Approximately two days later, the formation of blood vessels occurs within the embryo itself.
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...
The initial formation of this system is facilitated by the small amount of yolk present in the ovum and yolk sac. Blood vessels originate from...

