ファミリアルファエオクロモサイトーマにおける生殖系SDHD変異
Lancet (London, England)
|April 27, 2001
まとめ
SDHD遺伝子の遺伝子変異は,家族性ファエオクロモサイトーマと関連しています. SDHD変異の検査は,家族性,多発性,または早期発症のフェオクロモサイトーマを有する個人に推奨されます.
科学分野:
- エンドクリノロジー エンドクリノロジー
- 遺伝学 遺伝学とは
- 腫瘍学 腫瘍学
背景:
- ファミリアルファエオクロモサイトマの遺伝子は,ほとんど不明のままである.
- ファミリアルヘッド・アンド・ネックパラガングリオマは,サクシネート脱水原酶複合体のサブユニットD (SDHD) の遺伝子変異と関連しています.
- ファミリアルファエオクロモサイトーマの親類におけるSDHDの調査は正当化されています.
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