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Updated: Jun 5, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
09:04

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells

Published on: May 22, 2014

バクテリアのフラゲリンに対する先天的な免疫反応は,トール型受容体5によって媒介されます

F Hayashi1, K D Smith, A Ozinsky

  • 1Department of Immunology, University of Washington, Seattle 98195, USA.

Nature
|April 27, 2001
PubMed
まとめ

哺乳類のトール型受容体5 (TLR5) は,バクテリアのフラゲリンを検出し,フラゲル化された病原体の重要な成分です. この認識は,免疫信号伝達経路を活性化し,サイトカインの生産と細菌感染に対する効果的な免疫につながります.

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Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling

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