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TREM-1は炎症を増幅し,セプティックショックの重要な媒介者である

A Bouchon1, F Facchetti, M A Weigand

  • 1Basel Institute for Immunology, Grenzacherstrasse 487, CH-4005 Basel, Switzerland.

Nature
|April 27, 2001
PubMed
まとめ

ミエロイド細胞-1 (TREM-1) に発現するトリガリング受容体は,細菌感染に対する先天的な免疫反応を強化する. TREM-1を阻害すると,セプティックショックから保護され,治療の可能性が示されます.

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