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Updated: Jun 26, 2026

Examining BCL-2 Family Function with Large Unilamellar Vesicles
08:35

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Published on: October 5, 2012

プロアポプトティックBAXとBAK:ミトコンドリア機能障害と死亡への必要なゲートウェイ

M C Wei1, W X Zong, E H Cheng

  • 1Howard Hughes Medical Institute, Departments of Pathology and Medicine, Harvard Medical School, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

Science (New York, N.Y.)
|April 28, 2001
PubMed
まとめ

BAXまたはBAKタンパク質の活性化は,ミトコンドリア機能障害と細胞死を開始するために不可欠です. BAXとBAKの両方が欠けている細胞は,複数のアポプトシス刺激に抵抗し,アポプトシスにおける重要な役割を強調します.

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