関連する実験動画

Updated: Jun 29, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
10:27

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells

Published on: March 9, 2012

TIP4747による受容体徴募を促進するRab9 GTPaseの役割

K S Carroll1, J Hanna, I Simon

  • 1Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305-5307, USA.

Science (New York, N.Y.)
|May 19, 2001
PubMed
まとめ

TIP47は活性Rab9 GTPaseと結合し,マノース6リン酸受容体 (MPR) に対する afinityを高めます. この相互作用は,MPRの効率的なエンドソームからゴルギへの輸送に不可欠であり,貨物選択をRab GTPase活動と結びつける.

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