関連する実験動画
Updated: Jul 9, 2026
10:41
Identifying Amino Acid Overproducers Using Rare-Codon-Rich Markers
Published on: June 24, 2019
ブロヒビチン3'の未翻訳領域における単一核酸多形態化と乳がんに対する感受性
Lancet (London, England)
|May 30, 2001
まとめ
プロビビチン遺伝子変異 (Tアレル) は,特に家族歴のある若い女性において,乳がんのリスクの増加と関連しています. プロビチン遺伝子型決定は,このグループにおける乳がん早期リスク評価に役立ちます.
科学分野:
- 遺伝学 遺伝学とは
- 分子生物学は分子生物学である.
- 腫瘍学 腫瘍学
背景:
- プロビバチン遺伝子の3'未翻訳領域RNAは,G1からS段階への移行を阻害することによって,細胞サイクル進行を調節する.
- 変異性アレル (Tアレル) は,不活性なプロビビチン産物となり,細胞増殖制御に潜在的に影響を与える.
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When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...