関連する実験動画

Updated: Jun 28, 2026

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
12:59

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes

Published on: September 27, 2013

IL-12依存性の選択の前にTH1細胞の結合におけるTベットの役割

A C Mullen1, F A High, A S Hutchins

  • 1Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6160, USA.

Science (New York, N.Y.)
|June 9, 2001
PubMed
まとめ

T-betは,染色体を再構成し,IL-12受容体発現を誘導することによって,ヘルパーT (TH) 細胞のTH1細胞への分化を開始します. その後,インターリューキン-12 (IL-12) / STAT4はTH1細胞の生存を促進し,インターフェロン-ガンマ (IFN-ガンマ) の持続的な生産を促進します.

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