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ブラディキニンと神経成長因子は,PtdInsからカプサイシン受容体を放出します

H H Chuang1, E D Prescott, H Kong

  • 1Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California 94143-0450, USA.

Nature
|June 22, 2001
PubMed
まとめ

ブラディキニンと神経成長因子 (NGF) は,特定の受容体とフォスフォリファースC (PLC) 信号伝達を活性化することによって痛みを感知させます. このプロセスは,VR1熱で活性化されたイオンチャネルを必要とし,痛みの過敏性に対する分子機構を明らかにします.

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