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Updated: Jan 19, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

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ATR/ATM媒介によるヒトRad17のリン酸化は,遺伝子毒性ストレス反応に必要である

S Bao1, R S Tibbetts, K M Brumbaugh

  • 1Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

Nature
|June 22, 2001
PubMed
まとめ

遺伝子毒性ストレスは,DNA修復のための細胞サイクルチェックポイントを活性化します. ATM/ATRキナーゼによるヒトRad17 (hRad17) リン酸化は,このDNA損傷反応において決定的であり,細胞サイクル停止とDNA修復シグナリングを調節する.

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