アチピカルな右心房のパターン
1Cardiovascular Research Institute and Section of Cardiac Electrophysiology, University of California, San Francisco, USA.
Circulation
|June 27, 2001
まとめ
非典型的右心房振動 (AFL) は,下回路再入場のような近道に依存する回路を多く含む. 湿原に依存しないメカニズムには,上部のループの再入力または傷痕関連の回路が含まれます.
科学分野:
- 心臓病学 心臓病学
- 電気生理学 電気生理学
- 心律不整症とは,心律不整症のこと.
背景:
- アチピカル右心房振動 (AFL) は複雑な心拍不良です.
- 発症率と根本的なメカニズムを理解することは,効果的な治療に不可欠です.
研究 の 目的:
- flutterの患者における非典型の右側AFLの頻度を測定する.
- 非典型的右翼AFLを駆動する特定の電気生理学的メカニズムを解明する.
主な方法:
- 連続した372人の心房を患った患者の遡及的分析.
- 詳細な電気生理学的マッピングにより,再入気回路と突破部位を特定する.
主要な成果:
- 非典型的右側AFLは,患者の8% (28/372) で発生し,36回のエピソードが記録されています.
- Lower loop reentry (LLR) が最も一般的なメカニズム (67%) であり,突破口は三環にある.
- アッパー・ループの再入力と傷痕関連の回路は,あまり一般的なメカニズムではありませんでした.
結論:
- 非典型の右側AFLは,主としてLLRである,間隔に依存した再侵入と頻繁に関連しています.
- 上のループの再入場や傷跡関連の回路を含む,地溝に依存しないメカニズムも,非典型の右側AFLに寄与する.
- イストムスブロックをターゲットにすることで,LLRを排除し,潜在的な治療戦略を提供することができます.
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