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Updated: May 3, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
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成長因子の誘発によるRasとRap1の活性化の時空画像

N Mochizuki1, S Yamashita, K Kurokawa

  • 1Department of Structural Analysis, National Cardiovascular Center Research Institute, 5-7-1 Fujishirodai, Suita-shi, Osaka 565-8565, Japan.

Nature
|June 29, 2001
PubMed
まとめ

この研究では,光共振エネルギー転送 (FRET) センサーを使用して,細胞内のRasとRap1タンパク質の活性化を視覚化しています. 細胞のシグナル伝達と分化に不可欠な明確な空間的活性化パターンを明らかにします.

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