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Updated: Jun 18, 2026

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes
11:42

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes

Published on: November 1, 2012

単一鎖DNA分子を持つIA型DNAトポイソメラーゼの複合体の結晶構造

A Changela1, R J DiGate, A Mondragón

  • 1Department of Biochemistry, Molecular Biology and Cell Biology, Northwestern University, Evanston, Illinois 60208, USA.

Nature
|June 29, 2001
PubMed
まとめ

研究者らは,ssDNAと複合した無活性DNAトポイソメラーゼIII変異体の結晶構造を決定した. これは,酵素がどのように形を変えてDNAを結合するかを明らかにし,DNAトポロジーの調節に関する洞察を提供します.

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