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Updated: Jun 21, 2026

The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis
19:16

The Importance of Correct Protein Concentration for Kinetics and Affinity Determination in Structure-function Analysis

Published on: March 18, 2010

ポリケチド合成酵素モジュール間の中間物質のチャネリングにおけるタンパク質-タンパク質相互作用と酵素-基板相互作用のバランスを評価する

N Wu1, S Y Tsuji, D E Cane

  • 1Departments of Chemistry, Chemical Engineering, and Biochemistry, Stanford University, Stanford California 94305, USA.

Journal of the American Chemical Society
|July 6, 2001
PubMed
まとめ

ポリケチド合成酵素 (PKS) での基板チャネリングは,特に貧しい基板の場合,モジュールの効率を大幅に高めます. このメカニズムにより,PKSモジュールはより広い範囲の基板を処理することができ,組み合わせ生物合成の可能性を解き放ちます.

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