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Updated: May 9, 2026

Isolation and Culture of Neonatal Mouse Cardiomyocytes
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アルドステロンは,培養された新生児ラット心臓細胞におけるアンジオテンシン変換酵素の遺伝子発現を誘導する

E Harada1, M Yoshimura, H Yasue

  • 1Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Japan.

Circulation
|July 12, 2001
PubMed
まとめ

アルドステロンは,心臓細胞のアンジオテンシン変換酵素 (ACE) mRNAを増加させ,このプロセスはスピロノラクトンによって阻害されます. これは,スピロノラクトンが心不全の進行を管理するのに役立つ可能性があることを示唆しています.

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