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Updated: Aug 1, 2026

The MultiBac Protein Complex Production Platform at the EMBL
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エリトロマイシンポリケチド合成酵素による16基のマクロリドの前駆体誘導生物合成

K Kinoshita1, P G Williard, C Khosla

  • 1Department of Chemistry, Box H, Brown University, Providence, Rhode Island 02912-9108, USA.

Journal of the American Chemical Society
|July 18, 2001
PubMed
まとめ

Streptomyces coelicolorの変異した6-デオキシエリトロノリドB合成酵素は,トリケチドアナログを受け入れ,オクタケチドマクロラクトンを形成した. これは,ポリケチド合成酵素の基板特異性と新しいマクロラクトン生物合成に関する洞察を明らかにします.

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