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Updated: Jun 24, 2026

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
10:58

Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules

Published on: July 25, 2013

アラニンラセマゼにおける酵素基板相互作用のモデル.

M J Ondrechen1, J M Briggs, J A McCammon

  • 1Department of Chemistry, Northeastern University, Boston, Massachusetts 02115-5000, USA.

Journal of the American Chemical Society
|July 18, 2001
PubMed
まとめ

この研究では,アラニンラセメーゼをモデル化し,Tyr265'やLys39.9のような主要残基の異常な充電状態を明らかにしています. これらの発見は,L-アラニンとD-アラニンの変換における触媒基としての役割を支持し,酵素機構の理解を助けます.

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