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Updated: Jun 30, 2026

Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction
11:02

Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction

Published on: September 14, 2018

強力な抗腫瘍抗生物質,フレデリカマイシンAのエナチオセレクティブ全合成

Y Kita1, K Higuchi, Y Yoshida

  • 1Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamada-oka, Suita, Osaka 565-0871, Japan.

Journal of the American Chemical Society
|July 18, 2001
PubMed
まとめ

研究者は,抗腫瘍抗生物質のフレデリカマイシンAの非対称的全合成を詳細に説明しました. 研究は,キラルスパイロ炭素センターを含む複雑な構造の作成に焦点を当て,自然化合物の絶対的な構成を決定しました.

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