関連する実験動画

Updated: May 11, 2026

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses
14:23

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses

Published on: August 31, 2014

HIV感染における安定したCTL脱出変異の進化と伝播

P J Goulder1, C Brander, Y Tang

  • 1Partners AIDS Research Center, Massachusetts General Hospital and Division of AIDS, Harvard Medical School, Boston, Massachusetts 02114, USA. goulder@helix.mg.harvard.edu

Nature
|July 19, 2001
PubMed
まとめ

細胞毒性Tリンパ球 (CTLs) はHIV-1を制御しますが,感染中に脱出変異が生じることがあります. これらの突然変異,特にHLA-B27の制限されたエピトープでは,ウイルス制御に影響を与え,HIVワクチンの設計にも影響を及ぼします.

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