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Updated: May 13, 2026

Genetic Manipulation of Cerebellar Granule Neurons In Vitro and In Vivo to Study Neuronal Morphology and Migration
09:07

Genetic Manipulation of Cerebellar Granule Neurons In Vitro and In Vivo to Study Neuronal Morphology and Migration

Published on: March 18, 2014

ユビキチネーションに依存するメカニズムは,シナプスの成長と機能を調節する

A DiAntonio1, A P Haghighi, S L Portman

  • 1Department of Molecular Biology and Pharmacology, Washington University School of Medicine, 660 S. Euclid, Campus Box 8103, St Louis, Missouri 63110, USA. dianton@pcg.wustl.edu

Nature
|July 27, 2001
PubMed
まとめ

ユビキチン依存メカニズムはシナプスの発達を制御する. ニューロンのデウビキチン化プロテアゼを阻害すると,シナプスの過剰成長と機能障害が発生し,ユビキチン化調節体のバランスが重要なことを示唆しています.

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