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Updated: Jun 24, 2026

Analysis of RNA Processing Reactions Using Cell Free Systems: 3' End Cleavage of Pre-mRNA Substrates in vitro
09:16

Analysis of RNA Processing Reactions Using Cell Free Systems: 3' End Cleavage of Pre-mRNA Substrates in vitro

Published on: May 3, 2014

RPAは,オカザキの断片を真核生物で処理する際のエンドヌクレアスのスイッチングを制御する

S H Bae1, K H Bae, J A Kim

  • 1National Creative Research Initiative Center for Cell Cycle Control, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, 300 Chunchun-Dong, Changan-Ku, Suwon, Kyunggi-Do 440-746, Korea.

Nature
|July 27, 2001
PubMed
まとめ

DNA複製中のRNAプライマーの除去には,複製タンパク質-A (RPA) によって導かれるDna2とFen1核酸の協調的な作用が必要です. このプロセスは,真核生物の場合は原核生物よりも複雑で,オカザキの断片の成熟のための新しいメカニズムが含まれています.

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