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Updated: Jun 30, 2026

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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スプレッドは,Ras信号伝達のSprouty関連の抑制剤である

T Wakioka1, A Sasaki, R Kato

  • 1Division of Molecular and Cellular Immunology, Medical Institute of Bioregulation, Kyushu University, Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.

Nature
|August 9, 2001
PubMed
まとめ

スプレッドタンパク質は,Ras-MAPキナーゼ経路を阻害することによって,細胞の分化を調節する. Rasと相互作用し,Rafの活性化を抑制し,細胞成長信号を制御する.

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