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Updated: Jul 5, 2026

Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution
13:47

Enhanced Reduced Representation Bisulfite Sequencing for Assessment of DNA Methylation at Base Pair Resolution

Published on: February 24, 2015

哺乳類のエピジェネティクスにおけるDNAメチレーションの役割

P A Jones1, D Takai

  • 1USC/Norris Comprehensive Cancer Center, Departments of Biochemistry and Molecular Biology, Keck School of Medicine of the University of Southern California, 1441 Eastlake Avenue, MS 8302L, Los Angeles, CA 90089-9181, USA. jones_p@ccnt.hsc.usc.edu

Science (New York, N.Y.)
|August 11, 2001
PubMed
まとめ

哺乳類のゲノムは,非コーディングDNAを静止するためにサイトシンメチレーションを使用し,遺伝子発現の調節を確保します. この表遺伝的メカニズムは,プロモーターが活性化しながら,重複する要素や転置可能な要素を抑制することを可能にします.

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Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors06:07

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors

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