Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Translation01:31

Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Translation01:31

Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Translation01:31

Translation

Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Initiation of Translation02:33

Initiation of Translation

Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
Translation01:31

Translation

Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Proteins are called the...
Translation in Prokaryotes01:29

Translation in Prokaryotes

Prokaryote translation is a complex, highly coordinated process that converts genetic information from mRNA into functional proteins. It involves three stages: initiation, elongation, and termination, each facilitated by specific molecular components.Initiation of TranslationThe process begins with the assembly of the ribosomal subunits and initiation factors on the mRNA. In bacteria, the 30S ribosomal subunit recognizes the Shine-Dalgarno sequence in the mRNA, a conserved region upstream of...

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Repeat to gene expression ratios in leukemic blast cells can stratify risk prediction in acute myeloid leukemia.

BMC medical genomics·2021
Same author

Reading between the Lines: "ADD"-ing Histone and DNA Methylation Marks toward a New Epigenetic "Sum".

ACS chemical biology·2018
Same author

HIRA and Daxx constitute two independent histone H3.3-containing predeposition complexes.

Cold Spring Harbor symposia on quantitative biology·2010
Same author

Linking the epigenetic 'language' of covalent histone modifications to cancer.

British journal of cancer·2007
Same author

Histone chaperone Asf1 is required for histone H3 lysine 56 acetylation, a modification associated with S phase in mitosis and meiosis.

Proceedings of the National Academy of Sciences of the United States of America·2006
Same author

The role of histone modifications in epigenetic transitions during normal and perturbed development.

Ernst Schering Research Foundation workshop·2006
Same journal

Erratum for the Research Article "Detecting supramolecular organic nanoparticles during heat wave".

Science (New York, N.Y.)·2026
Same journal

Local signals, systemic decline.

Science (New York, N.Y.)·2026
Same journal

The mechanics of liver regeneration.

Science (New York, N.Y.)·2026
Same journal

Computing in a memory with physics.

Science (New York, N.Y.)·2026
Same journal

Retraction.

Science (New York, N.Y.)·2026
Same journal

Making time.

Science (New York, N.Y.)·2026
関連記事をすべて見る

関連する実験動画

Updated: Jun 10, 2026

Polysome Fractionation and Analysis of Mammalian Translatomes on a Genome-wide Scale
10:56

Polysome Fractionation and Analysis of Mammalian Translatomes on a Genome-wide Scale

Published on: May 17, 2014

ヒストンコードの翻訳

T Jenuwein1, C D Allis

  • 1Research Institute of Molecular Pathology (IMP) at the Vienna Biocenter, Dr. Bohrgasse 7, A-1030 Vienna, Austria. jenuwein@nt.imp.univie.ac.at

Science (New York, N.Y.)
|August 11, 2001
PubMed
まとめ
この要約は機械生成です。

ヒストンの翻訳後の改変は",ヒストンコード"を作り,遺伝子の活性を調節し,細胞の発達に影響を与えます. このエピジェネティックシステムは,ほとんどのクロマチンテンプレートプロセスに影響を与え,細胞の運命や病気に影響を与えます.

さらに関連する動画

Xenopus laevis as a Model to Identify Translation Impairment
10:24

Xenopus laevis as a Model to Identify Translation Impairment

Published on: September 27, 2015

De novo Identification of Actively Translated Open Reading Frames with Ribosome Profiling Data
08:23

De novo Identification of Actively Translated Open Reading Frames with Ribosome Profiling Data

Published on: February 18, 2022

関連する実験動画

Last Updated: Jun 10, 2026

Polysome Fractionation and Analysis of Mammalian Translatomes on a Genome-wide Scale
10:56

Polysome Fractionation and Analysis of Mammalian Translatomes on a Genome-wide Scale

Published on: May 17, 2014

Xenopus laevis as a Model to Identify Translation Impairment
10:24

Xenopus laevis as a Model to Identify Translation Impairment

Published on: September 27, 2015

De novo Identification of Actively Translated Open Reading Frames with Ribosome Profiling Data
08:23

De novo Identification of Actively Translated Open Reading Frames with Ribosome Profiling Data

Published on: February 18, 2022

科学分野:

  • 分子生物学は分子生物学である.
  • エピジェネティクス エピジェネティクス
  • 遺伝学 遺伝学とは

背景:

  • クロマチンは,真核生物の遺伝情報のテンプレートとして機能します.
  • ヒストンのアミノ端末は,翻訳後の修正を受けます.
  • これらの改変は,DNAのアクセシビリティと遺伝子発現を調節する.

研究 の 目的:

  • クロマチンの状態を調節するヒストンの改変の役割を調査する.
  • A の概念を導入する.
  • ヒストンのコード
  • 遺伝情報を拡張するものです.
  • 細胞プロセスにおけるこの表遺伝子マーキングシステムの重要性を強調する.

主な方法:

  • ヒストンのアミノ端末変異の分析.
  • タンパク質とクロマチンの相互作用の調査.
  • クロマチンの状態の検査 (アクティブとサイレント).

主要な成果:

  • 異なるヒストンの改変により,クロマチン関連タンパク質に対する様々な親和性が生まれます.
  • これらの相互作用は,アクティブクロマチンとサイレントクロマチンの間の移行を促します.
  • 結合ヒストンの改変は複雑な規制コードを形成する.

結論:

  • "ヒストーンコード"は,根本的な表遺伝的規制メカニズムである.
  • このシステムは,ほぼすべてのクロマチンのテンプレート化されたプロセスに影響を与えます.
  • 細胞の運命を左右し,細胞の発達や病気に重大な影響を及ぼします.