彼の電図の交代は,彼の波長の束の中の二重波長の入力と縦断の解離を明らかにします

Y Zhang¹, S Bharati, K A Mowrey

¹Department of Cardiology, the Cleveland Clinic Foundation, Cleveland, Ohio, 44195, USA.

Circulation

|August 15, 2001

まとめ

彼の電図 (HE) の交替は,心房心房節 (AVN) の明確な高速と遅い波面を明らかにします. これは,AVN内の機能的な解離を示し,再発性不律症を理解するのに役立ちます.

科学分野:

心血管電気生理学心血管電気生理学
心臓の解剖学と生理学

背景:

アトリオベントリキュラーノダル (AVN) 伝導の移行時に,His electrogram (HE) の振幅と形態の変化を観察した.
これらのHE変化がダブルAVN電気生理学に与える意義は十分に理解されていません.

研究の目的:

AVN伝導のシフト中に彼の電図の特徴が変化する現象を調査するために.
二重AVN電気生理学におけるこれらの変化の役割と,不律症との潜在的な関連を解明する.

主な方法:

プログラムされた電気ペースを用い,ウサギのアトリアル-AVN製剤の実験.
表面電極で彼の束に沿って彼の電図 (HE) のマッピング.
興奮波面を特定するために,細胞行動ポテンシャル (AP) の記録.

主要な成果:

上位HisバンドルHEsは,早発のビート中に振幅が減ったが,下位HEsは著しく増加した.
上部および下部HE活性化のシーケンスにおける時間的なシフトが観察され,伝導速度の変化と相関していました.
セルラー録音は,HEの変数と関連した明確な高速と遅い興奮波線の存在を確認した.

結論:

証拠は,Hisバンドルへの異なる高速と遅い波線の到着により,AV交差点内の機能的縦断を2つの領域に分割することを示唆しています.
特徴的なHEアルターナンは,異なる波線の敏感な指標として機能し,不規則なリズムにそれらの関与を意味します.
この発見は,二重AVN電気生理学の基礎となるメカニズムの理解を深める.

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