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Updated: Jun 22, 2026

Dissecting Host-virus Interaction in Lytic Replication of a Model Herpesvirus
11:28

Dissecting Host-virus Interaction in Lytic Replication of a Model Herpesvirus

Published on: October 7, 2011

エプスタイン・バルウイルスのORPからの複製にはヒトのORCが必要であり,ジェミニンによって抑制されます

S K Dhar1, K Yoshida, Y Machida

  • 1Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

Cell
|August 18, 2001
PubMed
まとめ

ORC2遺伝子の変異により,Orc2タンパク質が減少し,細胞サイクルが延長されたが,細胞DNA複製の起源には影響はなかった. エプスタイン・バーウイルスの起源 (oriP) から発生するウイルスの複製が阻害され,ORCが示されました.

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