血液/傷害恐怖症の被験者において,血管管内麻痺の予備性
V Accurso1, M Winnicki, A S Shamsuzzaman
1Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Circulation
|August 22, 2001
まとめ
血液/傷害恐怖症の個人は,自律的調節障害のためにしばしば昏睡する. この研究は,彼らがトリガーなしでも,ヘッド・アップ・ティルトの際に血管性失眠に罹患する傾向があることを示しています.
科学分野:
- 生理学 生理学とは
- 自律神経系とは
- 精神生理学 精神生理学とは
背景:
- 血液/傷害の恐怖症は,しばしば昏睡または前昏睡と関連しています.
- 自律的調節不全は,これらの個体において,血管道筋梗塞の予備因子であると仮定されています.
研究 の 目的:
- 血液/傷害恐怖症の被験者は,立憲的自律失調症を持っているという仮説を検証する.
- この集団におけるヘッド・アップ・ティルトの時の血管管内麻痺の予備性を調査する.
主な方法:
- 血液/傷害恐怖症によって誘発された気絶症と11人の健康な対照群を研究した.
- 血圧と心拍数は15分間のベースラインと45分間のヘッドアップの傾きで70度までモニタリングされました.
主要な成果:
- 血恐怖症の被験者の82%が,傾き時のプレシンコプまたはシンコプを経験し,対照群の9%と比較した (P=0.001).
- 血恐怖症の被験者は,静脈血管反応を示し,傾き時の静脈血圧 (21 mmHg) と心拍数 (22 bpm) の有意な低下を示した.
- コントロール被験者は,ヘッド・アップ・ティルトの際に安定した血圧と心拍数を示した.
結論:
- 血液/傷害恐怖症の個人は,基礎にある自律的調節障害を示しています.
- この調節障害は,特定の恐怖刺激から独立して,神経媒介による昏睡に誘導します.
- 繰り返し起こるシンコパルイベントは,血液/傷害恐怖症の発達または悪化に寄与する可能性があります.
キーワード:
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