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Updated: Jun 20, 2026

Retroviral Transduction of Helper T Cells as a Genetic Approach to Study Mechanisms Controlling their Differentiation and Function
11:50

Retroviral Transduction of Helper T Cells as a Genetic Approach to Study Mechanisms Controlling their Differentiation and Function

Published on: November 4, 2016

選択的転写と静止T細胞活動の調節は, HIVのDNAがプリインテグレートされていることによって行われます

Y Wu1, J W Marsh

  • 1Laboratory of Molecular Biology, National Institute of Mental Health, Bethesda, MD 20892-4034, USA.

Science (New York, N.Y.)
|August 25, 2001
PubMed
まとめ

ヒト免疫不全ウイルス (HIV) は,ウイルスのDNA統合前に,NEFとTAT遺伝子を活性化することによって,休息しているT細胞で複製することができます. この前統合転写はT細胞の活性化とウイルスの拡散を促します.

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