妊婦のエネルギー貯蔵と妊娠中の食事組成 プログラム 青少年 血圧
L S Adair1, C W Kuzawa, J Borja
1Department of Nutrition, Schools of Public Health and Medicine, University of North Carolina, Chapel Hill, NC 27516-3997, USA. linda_adair@unc.edu
Circulation
|August 29, 2001
まとめ
妊娠中の母親の栄養は,青少年の血圧 (BP) に影響を及ぼします. 特定の食事成分と母親の脂肪貯蔵は,子孫のBPに影響を及ぼし,長期の心血管健康のために産前栄養の重要性を強調しています.
科学分野:
- 栄養学的流行病学について
- 健康と病気の発達の起源 (DOHaD)
- 心血管の健康についてです.
背景:
- 胎児の栄養不良は,後年における血圧 (BP) のプログラム化に関連しています.
- 胎児の栄養不良のプロキシとして出生体重を使用する既存の疫学研究は,母親の栄養因子に関する特異性がない.
- 精密な母子の栄養的影響を特定することは,長期的なBPプログラミングを理解するために不可欠です.
研究 の 目的:
- 妊娠中の母親の栄養と青少年の血圧 (BP) の関係を調べる.
- 母親の食事組成 (エネルギー,タンパク質,脂肪) と母親の肥満が子孫に与える影響を調べる.
- 赤ちゃんの出生体重が,母親の栄養と青少年のBPに関連して果たす役割を評価する.
主な方法:
- 2026年フィリピン人の青少年を対象とした前向きなコホート研究 (Cebu longitudinal health and nutrition survey).
- 妊娠中に評価された母親の栄養状態 (約. 30週間の妊娠期間) で,食事による摂取量と三頭筋の皮のの厚さを含みます.
- 青春期のシストリックおよびダイアストリックBP (SBPとDBP) は,回帰モデルを使用して測定および分析され,混同因子を制御しました.
主要な成果:
- 母親の三頭筋の皮のの厚さは,男の子のSBPと男女のDBPと逆に関連していました.
- 母親のタンパク質摂取量は,男の子のSBPと逆相関しており,母親の脂肪摂取量は,女の子のSBPとDBPと逆相関していました.
- 母親の栄養的要因は,男の子の出生体重とSBPの逆関係を部分的に弱めた.
結論:
- 妊娠中の母親の食事の組成は,子供の青年の血圧に大きな影響を与えます.
- 母親の皮下脂肪貯蔵 (三頭体皮のの厚さ) は,子孫の長期的なBP規制と関連しています.
- これらの発見は,胎児の心血管健康をプログラムする上で,母親の栄養と体の組成が果たす重要な役割を強調しています.
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