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Updated: Jul 16, 2026

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
11:19

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels

Published on: July 4, 2016

サイクリックヌクレオチドゲートチャネル開通時の回転運動

J P Johnson1, W N Zagotta

  • 1Howard Hughes Medical Institute & Department of Physiology and Biophysics, University of Washington School of Medicine, Seattle 98195, USA.

Nature
|August 31, 2001
PubMed
まとめ

ニッケルイオン (Ni2+) は,感覚信号に不可欠なサイクルヌクレオチドゲート (CNG) チャンネルを調節する. C-リンカー領域の特定のヒスティジン残基は,Ni2+がチャネル活動を強化するか抑制するかを決定し,ゲーティングメカニズムに関する洞察を明らかにします.

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