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Updated: May 12, 2026

Programmed Electrical Stimulation in Mice
07:29

Programmed Electrical Stimulation in Mice

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SCN5A関連不律症候群におけるフレカニド作用のゲート依存メカニズム

P C Viswanathan1, C R Bezzina, A L George

  • 1Department of Anesthesiology, Vanderbilt University, Nashville, Tennessee, USA.

Circulation
|September 6, 2001
PubMed
まとめ

心臓ナトリウムチャネル (SCN5A) 変異は,LQT3およびブルガダ症候群を引き起こす. これらの変異における無活性化ゲーティングの欠陥は,フレカニドに対する感受性を高め,危険な不律を潜在的に引き起こします.

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