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Updated: May 3, 2026

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
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マル (MyD88型アダプター型) は,Toll型受容体-4の信号伝導に必須です

K A Fitzgerald1, E M Palsson-McDermott, A G Bowie

  • 1Department of Biochemistry, Trinity College, Dublin 2, Ireland.

Nature
|September 7, 2001
PubMed
まとめ

新しく特定されたタンパク質であるMal (MyD88-adapter-like) は,Toll-like receptor-4 (TLR-4) 信号伝達において重要なアダプタとして作用する. マルは,下流の信号伝達経路を媒介することによって,グラム陰性細菌に対する先天的な免疫反応を促進します.

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