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Updated: Jun 26, 2026

Single-molecule Imaging of Gene Regulation In vivo Using Cotranslational Activation by Cleavage (CoTrAC)
11:31

Single-molecule Imaging of Gene Regulation In vivo Using Cotranslational Activation by Cleavage (CoTrAC)

Published on: March 15, 2013

CREBは,コアクティベーターPGC-1を通じて肝臓のグルコネオゲネシスを調節する

S Herzig1, F Long, U S Jhala

  • 1Peptide Biology Laboratories, Salk Institute for Biological Studies, 10010 N Torrey Pines Road, La Jolla, California 92037-1002, USA.

Nature
|September 15, 2001
PubMed
まとめ

循環型AMP (cAMP) 応答要素結合 (CREB) タンパク質は,グルコン生成の重要な要因であるPGC-1を活性化することによって,断食中のグルコースホメオスタシスを調節する. この経路は,断食中の低血糖症の予防に不可欠であり,II型糖尿病に関与している可能性があります.

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