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c-Junは,肺動脈の滑らかな筋肉細胞の電圧ゲートされたK (((+)) チャンネル活動を低下させます

Y Yu1, O Platoshyn, J Zhang

  • 1Department of Medicine, University of California, San Diego, San Diego, CA 92103-8382, USA.

Circulation
|September 26, 2001
PubMed
まとめ

転写因子c-Junは,肺動脈の滑らかな筋肉細胞 (PASMCs) の電圧誘導カリウムチャンネル (K(v)) 活動を減少させます. このK ((v)) 流の減少は,膜の去極化,カルシウムの増加,およびPASMCの増殖を促進します.

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