まとめ
心肺バイパス中に心臓を鼓動し,機能しない状態に保つことは,ミトラ弁置換術 (MVR) の後の結果を大幅に改善します. この方法は,イノトロプ的サポートの必要性を減らし,従来の方法と比較して死亡率を下げます.
科学分野:
- 心血管外科手術についてです.
- 心臓の保存について
- 心筋筋機能の性能について
背景:
- ミトラル弁置換 (MVR) は,心肺バイパス手術中に効果的な心臓保存技術を必要とします.
- 以前の方法では,長時間不血性停止または輸血による心室細動が伴うが,手術後の心筋機能が最適以下であることが示された.
研究 の 目的:
- MVR中の異なる心臓保存戦略の有効性を比較する.
- 心肺バイパス手術中に心筋膜の保存のための最適な状態を決定する.
主な方法:
- 1968年から1974年の間にMVRを受けた2つの患者グループを遡って比較した.
- グループI:深度の局所性低体温と不血症停止または静脈動と輸血による心臓保存 (n=47).
- グループII: 短期的な不血性停止期間 (n=22) の間に,鼓動する,非作業状態の心臓の保存.
主要な成果:
- グループIは55%のイノトロピックサポーティングの必要性と17%の死亡率を経験しました.
- グループIIは,イノトロピックサポーティングの必要性 (5%) と死亡率 (5%) が著しく低下した.
- グループIIの単一の死亡は,保存方法ではなく,手術中の合併症に起因した.
結論:
- MVRの間に心臓を鼓動し,非作業状態に保つことは,術後の心筋機能の維持に優れています.
- 輸液による長期発血不全と心室細動を回避することで,心筋のうつ状態を最小限に抑えることができます.
- このテクニックは,患者の回復を向上させ,ミトラル弁置換術後の死亡率を低減します.
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