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Updated: Jun 25, 2026

Isolation of Pulmonary Artery Smooth Muscle Cells from Neonatal Mice
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血管壁および高コレステロール血症ウサギの単核細胞における内皮酸化窒素合成酵素発現の調節

A Jiménez1, M M Arriero, A López-Blaya

  • 1Fundación Jiménez Díaz, Cardiovascular Research and Hypertension Laboratory, Madrid, Spain.

Circulation
|October 10, 2001
PubMed
まとめ

高コレステロール血症は,ENOS mRNAに結合する60kDaのタンパク質を介して,内皮酸化窒素合成酵素 (eNOS) の発現を低下させる. セリバスタチン治療は,ウサギではこれらの効果を逆転させ,内皮機能を改善しました.

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