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Updated: Jul 10, 2026

Production of Apolipoprotein C-III Knockout Rabbits using Zinc Finger Nucleases
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ヘム酸化酵素-1は,ワタナベの遺伝性高脂血症ウサギのアテロゲネシスを阻害する

K Ishikawa1, D Sugawara, J Goto

  • 1First Department of Internal Medicine, Fukushima Medical University, Fukushima, Japan.

Circulation
|October 10, 2001
PubMed
まとめ

ヘム酸化酵素-1 (HO-1) は,脂質過酸化を防止することによって,抗アテロゲン性を持つことを示しています. ウサギのHO-1を阻害すると,動脈硬化性病変の形成が著しく増加し,心臓血管疾患に対する保護的役割を強調しました.

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