SOFAスコアのシリアル評価は,重症患者の結果を予測するためのものです
F L Ferreira1, D P Bota, A Bross
1Department of Intensive Care, Erasme University Hospital, Route de Lennik, 808, B-1070 Brussels, Belgium. jlvincen@ulb.ac.be
JAMA
|October 12, 2001
まとめ
ICUでの繰り返し連続器官不全評価 (SOFA) のスコアは,患者の死亡率を予測します. 48時間以内にSOFAスコアが上昇すると,最初のスコアに関係なく,少なくとも50%の死亡リスクを示します.
科学分野:
- クリティカルケア・メディシン
- 予測バイオマーカー
- 集中治療室の成果について
背景:
- 臓器機能不全は重症患者の重要な要因である.
- 臓器機能不全の傾向を評価することは,結果を予測するのに役立ちます.
研究 の 目的:
- 集中治療室 (ICU) の患者の死亡率を予測するために,連続した臓器不全評価 (SOFA) のスコアの有用性を評価する.
- SOFAスコアトレンドが予測的価値を提供しているかどうかを判断する.
主な方法:
- ICU患者352人を対象とした前向きな観察コホート研究.
- SOFAのスコアは,入学時に,そして48時間ごとに計算されます.
- 死亡率に関連する初期,最高,平均,デルタ-SOFAスコアの分析.
主要な成果:
- SOFAスコア (初期,最高,平均) は死亡率と強く相関していた.
- 最高のSOFAスコアは,ROC曲線 (0.90) の下の最大の面積を示した.
- 96時間以内にSOFAスコアが上昇すると>50%の死亡率が予測され,スコアが低下すると<27%の死亡率が予測される.
結論:
- ICUでの連続的なSOFAスコア評価は,貴重な予後情報を提供します.
- 平均と最高SOFAスコアは,有効な結果予測指標です.
- 最初の48時間以内にSOFAスコアが上昇すると,高い死亡リスクが独立して予測されます.
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