妊娠検査の自然な限界は,予想される月経周期との関係です
A J Wilcox1, D D Baird, D Dunson
1Epidemiology Branch, MD A3-05, National Institute of Environmental Health Sciences, Durham, NC 27709, USA. wilcox@niehs.nih.gov
JAMA
|October 12, 2001
まとめ
妊娠検査は,月経が欠落した最初の日に,早期妊娠の10%を逃す可能性があります. 正確な早期妊娠検知のために,より高い感度のために1週間後にテストすることを検討してください.
科学分野:
- 生殖内分泌学 生殖内分泌学
- 臨床化学 臨床化学について
- 人間の生殖は,人間の生殖です.
背景:
- 標準的な妊娠検査では,月経が欠落した最初の日に使用することを推奨しています.
- 妊娠の早期発見は,芽細胞の植え付けタイミングによって制限されています.
- 排卵の変動性とは,予想される月経と比較してインプラントのタイミングが異なることを意味します.
研究 の 目的:
- 妊娠検査の最大スクリーニング感度を推定するために,月経が欠落した最初の日に.
- 排卵とインプラントのタイミングの自然な変動を考慮するために.
主な方法:
- ノースカロライナ州 (1982年−1986年) で実施されたコミュニティベースの前向きなコホート研究.
- 21歳から42歳の健康な女性221人が妊娠を計画しています.
- 連続した尿サンプルからヒト胆管性高原原素 (hCG) の検査を行い,予想される月経に対するインプランテーション日を決定します.
主要な成果:
- 臨床妊娠の10% (14/136) は,月経欠落の最初の日にインプラントを入れていない.
- hCG検査の推定最大スクリーニング感度は,月経欠落の最初の日に90%です.
- 感度が97%に増加するのは,月経欠落の最初の1日から1週間後です.
結論:
- 臨床妊娠の10%は,月経が欠落した最初の日に非常に敏感なhCG検査で検出できませんでした.
- 現在の商用試験での実際の検出率は,アッセイの制限により低い可能性があります.
- 生理欠落後1週間後に検査を行うことは,妊娠検出率を改善します.
関連する概念動画
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