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原子解像度における酵素メカニズムにおける共性中間物質の観察

A Heine1, G DeSantis, J G Luz

  • 1Department of Molecular Biology, Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|October 13, 2001
PubMed
まとめ

この研究では,原子解像度のX線構造を用いて,酵素反応の中間物質を明らかにしています. これは,陽子の移転を含む,d-2-デオキシリボース-5-リン酸 (DRP) アルドラーゼ触媒の重要なステップを特定します.

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