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Analytical Techniques for Assaying Nitric Oxide Bioactivity
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クロニジンの中心的な低血圧作用は,酸化窒素を必要とします

L W Dobrucki1, C L Cabrera, D F Bohr

  • 1Department of Chemistry, Ohio University, Athens, USA.

Circulation
|October 17, 2001
PubMed
まとめ

クロニジンは,脳内の酸化窒素 (NO) 産生を刺激することで血圧を下げる. この研究は,Nucleus tractus solitarius (NTS) でNOの放出が増加することが,クロニジンの抗高血圧効果の鍵であることを確認しています.

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