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Updated: May 5, 2026

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis
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Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis

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C/EBPalphaによるE2F抑制は,アディポゲネシスとグラヌロポエシス in vivoのために必要である

B T Porse1, Pedersen TA, X Xu

  • 1Laboratory of Gene Therapy Research, 2100 Copenhagen Ø, Denmark.

Cell
|October 24, 2001
PubMed
まとめ

CCAAT/強化剤結合タンパク質アルファ (C/EBPalpha) の転写因子である

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Tissue-specific transcription factors contribute to diverse cellular functions in mammals. For example, the gene for beta globin, a major component of hemoglobin, is present in all cells of the body. However, it is only expressed in red blood cells because the transcription factors that can bind to the promoter sequences of the beta globin gene are only expressed in these cells. Tissue-specific transcription factors also ensure that mutations in these factors may impair only the function of...
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