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Updated: Jul 23, 2026

Skeletal Muscle Gender Dimorphism from Proteomics
09:29

Skeletal Muscle Gender Dimorphism from Proteomics

Published on: December 14, 2011

骨格筋縮に必要なウビキチンリガゼの特定

S C Bodine1, E Latres, S Baumhueter

  • 1Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591-6707, USA.

Science (New York, N.Y.)
|October 27, 2001
PubMed
まとめ

研究者らは,骨格筋の縮を誘発するキータンパク質であるMuscle RING Finger 1 (MuRF1) とMuscle Atrophy F-box (MAFbx) を特定した. これらのタンパク質が欠けていたマウスは,筋肉の消耗に抵抗を示し,潜在的な薬物標的であることを示唆しました.

キーワード:
非プログラム的なものです.

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