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Updated: Jul 10, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
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NSAIDsのサブセットは,サイクロオキシゲネーゼの活性から独立して,アミロイド原性Abeta42を低下させる

S Weggen1, J L Eriksen, P Das

  • 1Department of Neurosciences, University of California San Diego, La Jolla, California 92093, USA.

Nature
|November 9, 2001
PubMed
まとめ

非ステロイド性抗炎症薬 (NSAIDs) は,アルツハイマー病の重要な要因であるアミロイドベータ42 (Abeta42) ペプチドのレベルを大幅に低下させます. このAbeta42の減少は,サイクロオキシゲネーゼ抑制とは無関係に発生し,新たな治療経路を示唆しています.

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