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Updated: Jul 6, 2026

Isolation of Precursor B-cell Subsets from Umbilical Cord Blood
14:06

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Published on: April 16, 2013

免疫系における非同期的な複製とアレル排除

R Mostoslavsky1, N Singh, T Tenzen

  • 1Department of Cellular Biochemistry & Human Genetics, and Experimental Medicine & Cancer Research, PO Box 12272, Hebrew University, Jerusalem 91120, Israel.

Nature
|November 9, 2001
PubMed
まとめ

成熟したB細胞の発達は,単一の抗原受容体を選択するためにアレル排除に依存しています. DNA複製のタイミングはエピジェネティックマークとして作用し,X染色体不活性化に類似して,早期複製アレルの再配置を好みます.

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