活性化されたインタースティシャルミオフィブロブラストは,カタボリック酵素を発現し,ミクソマトスの心弁のマトリックスリモデリングを媒介する

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Updated: Jul 9, 2026

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix
10:21

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix

Published on: June 14, 2016

E Rabkin1, M Aikawa, J R Stone

  • 1Department of Pathology, Leducq Center for Cardiovascular Research, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Circulation
|November 21, 2001
PubMed
まとめ

ミクソマトス型ミトラ弁変性における弁間細胞は,ミオフィブロブラストに変異する. これらの細胞は過度にカタボリック酵素を分泌し,影響を受けた心弁のマトリックス分解と再構成を促します.

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