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Updated: Jun 11, 2026

Peptides from Phage Display Library Modulate Gene Expression in Mesenchymal Cells and Potentiate Osteogenesis in Unicortical Bone Defects
07:53

Peptides from Phage Display Library Modulate Gene Expression in Mesenchymal Cells and Potentiate Osteogenesis in Unicortical Bone Defects

Published on: December 11, 2010

モデルペプチドアセチル-フェ-グライ-グライ-N-メチルアミドにおけるアロマティック・バックボーン・アミド相互作用の調査は,分子動態シミュレーションとタンパク質データベースの検索を用いて行われました

G Tóth1, R F Murphy, S Lovas

  • 1Department of Biomedical Sciences, School of Medicine, Creighton University, 2500 California Plaza, Omaha, Nebraska 68178, USA.

Journal of the American Chemical Society
|November 22, 2001
PubMed
まとめ

アロマティック・リング・バックボーン・アミド相互作用 (Ar-HN) は,特定のペプチド構造を安定させる. 分子ダイナミクスシミュレーションでは,これらの相互作用が溶媒のアクセシビリティと水素結合を低下させ,タンパク質構造に影響を及ぼすことを明らかにしています.

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