心筋病:遺伝学から治療の可能性まで

W M Franz1, O J Müller, H A Katus

  • 1Medizinische Klinik und Poliklinik Grosshadern, Klinikum der Universität München, München, Germany. wfranz@helios.med

Lancet (London, England)
|November 22, 2001
PubMed
まとめ

心筋病は,心臓の機能不全を引き起こす心筋膜疾患である. サルコメリックおよび細胞骨格タンパク質の遺伝子変異は,高縮性 (HCM),膨張性 (DCM) および不律性右心室性 (ARVC) 心筋病変の主要な要因であり,心臓機能に影響を与え,心不全または突然死につながる.

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