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Updated: Jan 8, 2026

Author Spotlight: Dendritic Cells Maturation Using Sialidases-Based Enzymatic Treatment of the Cell Surface
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Author Spotlight: Dendritic Cells Maturation Using Sialidases-Based Enzymatic Treatment of the Cell Surface

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CD8アルファベタ核受容体茎の発達的に調節されたグリコシライゼーションは,リガンド結合を調節する

A M Moody1, D Chui, P A Reche

  • 1Laboratory of Immunobiology, Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.

Cell
|November 24, 2001
PubMed
まとめ

細胞の分化により,CD8βのO-グリカンが変化し,T細胞受容体結合に影響を与えます. ST3Gal-I酵素は,これらのグリカンを改変し,T細胞の成熟時にCD8アルファベータ-MHCIアビデーションを減少させます.

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