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Updated: May 12, 2026

Mimicking the Function of Signaling Proteins: Toward Artificial Signal Transduction Therapy
12:24

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Published on: September 29, 2016

アルファ6ベータ4インテグリンに対するシグナリングアダプタは,HGF依存の侵入性成長の制御において機能する

L Trusolino1, A Bertotti, P M Comoglio

  • 1IRCC, Institute for Cancer Research and Treatment, University of Torino School of Medicine, 10060 (Torino), Candiolo, Italy. ltrusolino@ircc.unito.it

Cell
|December 6, 2001
PubMed
まとめ

アルファ6ベータ4インテグリンとメット受容体は,がんの侵入を強化するために協力します. Alpha6beta4は信号放大器として作用し,腫瘍の成長に不可欠なHGF駆動経路を強化します.

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